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[Experience with a selenium-containing biological active supplement used in children with pneumonias in an intensive

A K Uglitskikh, N B Tsokova, I V Gmoshinskiĭ

    Anesteziologiia I Reanimatologiia
    |April 15, 2006
    PubMed

    Insights

    The biologically active additive "Spirulin-Sochi-Selen" effectively treated acute pneumonia in pediatric intensive care patients. This selenium supplement improved clinical outcomes without causing deficiency signs.

    Area of Science:

    • Pediatrics
    • Clinical Nutrition
    • Pharmacology

    Background:

    • Acute pneumonia is a significant cause of pediatric critical illness.
    • Selenium is an essential trace element with immune-modulating properties.
    • Biologically active additives (BAAs) offer potential adjunctive therapies.

    Purpose of the Study:

    • To evaluate the efficacy of the BAA "Spirulin-Sochi-Selen" in children with acute pneumonia.
    • To assess the impact of the BAA on clinical, laboratory, functional, and radiological parameters.
    • To monitor selenium levels and identify any deficiency signs during treatment.

    Main Methods:

    • A study involving 45 children (3-15 years) with acute pneumonia in an intensive care unit.
    • Administration of the BAA "Spirulin-Sochi-Selen" as part of the treatment regimen.
    • A control group of 20 children received no selenium-containing supplements.
    • Selenium levels measured using the Alfthan microfluorimetric technique (1984).

    Main Results:

    • The BAA "Spirulin-Sochi-Selen" demonstrated efficacy in the therapeutic management of acute pneumonia.
    • Positive trends were observed in clinical, laboratory, functional, and X-ray assessments.
    • No signs of selenium deficiency were noted in any patient, despite baseline reductions.

    Conclusions:

    • "Spirulin-Sochi-Selen" can be effectively incorporated into the therapy for pediatric acute pneumonia in intensive care settings.
    • The BAA appears safe and does not exacerbate selenium deficiency.
    • Further research into selenium's role in pediatric respiratory infections is warranted.

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