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A very large, rapidly developing, congenital giant cell fibroblastoma in a 5-month old infant

Cihangir Aliağaoğlu1, Vedat Bakan, Mustafa Atasoy

  • 1Department of Dermatology, Numune State Hospital, Ezurum, Turkey. caliagaoglu@yahoo.com

The Journal of Dermatology
|April 20, 2006
PubMed

Insights

Giant cell fibroblastoma, a rare childhood soft tissue tumor, can present as a large, rapidly growing mass. This case highlights an unusually large lesion in a 5-month-old, suggesting a potential juvenile form of dermatofibrosarcoma protuberans.

Area of Science:

  • Pediatric Oncology
  • Dermatopathology
  • Soft Tissue Neoplasms

Background:

  • Giant cell fibroblastoma (GCF) is a rare soft tissue neoplasm primarily affecting children.
  • It is considered a potential juvenile counterpart to dermatofibrosarcoma protuberans (DFSP).
  • Congenital cases of GCF are exceedingly rare, with only one previously reported.

Observation:

  • This report details a 5-month-old female infant presenting with a rapidly growing mass on her right scapula.
  • The lesion exhibited atypical growth characteristics.
  • The mass measured an unusually large 12 cm x 10 cm x 8 cm.

Findings:

  • The observed GCF was significantly larger than any previously documented in the literature.
  • The rapid and atypical growth pattern in this infant warrants further investigation.
  • Histopathological analysis confirmed the diagnosis of giant cell fibroblastoma.

Implications:

  • This case expands the known size spectrum for pediatric giant cell fibroblastoma.
  • It underscores the importance of considering GCF in the differential diagnosis of rapidly growing pediatric soft tissue masses.
  • Further research may elucidate the relationship between GCF and DFSP, particularly in congenital or large presentations.

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