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Updated: Aug 9, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
Published on: July 29, 2007
[Dropped head syndrome in motor neuron disease]
Paulo José Lorenzoni1, Marcos Christiano Lange, Cláudia S K Kay
1Serviço de Neurologia e Doenças Neuromusculares, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Abstract:
Dropped head is a syndrome caused by weakness of the neck extensor muscles found in different kinds of neuromuscular disorders and also in amyotrophic lateral sclerosis. This is a cases report of three women with motor neuron disease with beginning of dysphagia and cervical weakness that it evolved with dropped head. The investigation showed normal magnetic resonance imaging of brain and cervical column. Needle electromyography showed active and chronic denervation in bulbar muscles and cervical, thoracic and lumbosacral segments. We discuss the characteristic of disease, specially the clinical manifestations and electromyography features, with emphasis at the clinical evaluation of dropped head in the suspicion of motor neuron disease.
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