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Updated: Aug 9, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

[Percutaneous coronary interventions in patients with ischemic heart disease and chronic renal failure]

Adam Witkowski1

  • 1Samodzielna Pracownia Hemodynamiki Instytutu Kardiologii w Warszawie. witkowski@hbz.pl

Przeglad Lekarski
|April 21, 2006
PubMed

Insights

Patients with chronic renal failure (CRF) undergoing percutaneous coronary interventions (PCI) for ischemic heart disease (IHD) face poor long-term survival. Coronary artery bypass graft (CABG) surgery may offer better long-term outcomes for select CRF patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Interventional Cardiology

Context:

  • Chronic renal failure (CRF) affects 10% of patients with ischemic heart disease (IHD) undergoing percutaneous coronary interventions (PCI).
  • CRF patients exhibit increased risks of major adverse cardiac events post-PCI.
  • While coronary stents improve prognosis, long-term survival remains suboptimal in this population.

Purpose:

  • To compare the efficacy and outcomes of percutaneous coronary interventions (PCI) versus coronary artery bypass graft (CABG) surgery in patients with chronic renal failure (CRF).
  • To evaluate the long-term survival and adverse event rates associated with different revascularization strategies in CRF patients with ischemic heart disease (IHD).

Summary:

  • Coronary artery bypass graft (CABG) surgery presents an alternative to PCI for CRF patients, offering potentially better long-term prognosis despite higher in-hospital mortality.
  • CABG is likely the preferred treatment for CRF patients with multivessel coronary artery disease, left main stenosis, or diabetes.
  • The impact of drug-eluting stents on long-term survival in CRF patients is currently undetermined.

Impact:

  • This analysis informs treatment decisions for ischemic heart disease (IHD) in patients with chronic renal failure (CRF).
  • Highlights the need for further research into optimal revascularization strategies, including the role of drug-eluting stents, for CRF patients.
  • Aims to improve long-term survival and reduce adverse cardiac events in this high-risk patient group.

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