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Updated: Aug 9, 2026

Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
A novel generation of indole-2,3-quinodimethanes
Norikazu Kuroda1, Yukie Takahashi, Kazuo Yoshinaga
1Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.
Abstract:
[reaction: see text] A novel and efficient procedure for the generation of the reactive indole-2,3-quinodimethane intermediates from the allenylanilines is described. The indole-2,3-quinodimethane intermediates were captured by several dienophiles to afford the corresponding tetrahydro- and dihydrocarbazole derivatives. This method is significantly different from the previously reported ones, which involve the 1,4-elimination or its related reactions of the indole derivatives that possess suitable substituents at both the C-2 and C-3 positions.
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