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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
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[Gastric acid reflux and reflux esophagitis in children]

Mi-zu Jiang1, Tian-lin Wang, Xue-lian Zhou

  • 1Department of Gastroenterology, Children's Hospital, Zhejiang Universtiy School of Medicine, Hangzhou 310003, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|April 21, 2006
PubMed

Insights

Gastric acid reflux is significant in pediatric reflux esophagitis (RE), but not the sole cause. The severity of acid reflux doesn't always correlate with RE severity, highlighting the importance of gastroscopy for diagnosis.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders
  • Esophageal Physiology

Background:

  • Reflux esophagitis (RE) is a common condition in children, often associated with gastroesophageal reflux (GER).
  • Understanding the role of gastric acid reflux in the pathogenesis of RE is crucial for effective management.
  • Previous studies have explored the link between acid reflux and RE, but further clarification in pediatric populations is needed.

Purpose of the Study:

  • To investigate the role of gastric acid reflux in the development of reflux esophagitis (RE) in children.
  • To analyze the relationship between acid reflux parameters and the severity of RE.
  • To determine the diagnostic importance of gastroscopy in children with reflux symptoms.

Main Methods:

  • A study involving 180 children presenting with vomiting.
  • Utilized 24-hour esophageal pH monitoring and gastroscopy to assess acid reflux and esophageal status.
  • Compared acid reflux parameters between children with RE, non-esophagitis (NE), and non-erosive reflux disease (NERD).

Main Results:

  • Reflux esophagitis was diagnosed in 65 of 180 children.
  • The positive rate of acid reflux was significantly higher in the RE group (58.5%) compared to the NE group (42.6%).
  • Acid reflux parameters did not consistently correlate with the severity of RE (grades I-III).

Conclusions:

  • Gastric acid reflux plays a significant role in pediatric RE but is not the sole contributing factor.
  • The degree of acid reflux does not directly correspond to the severity of RE.
  • Gastroscopy is essential for diagnosing and evaluating reflux symptoms in children.
Abstract

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