Free-breathing three-dimensional computed tomography of the lung using prospective respiratory gating: charge-coupled...

The aim was to investigate the feasibility and image quality of prospective respiratory gating for 3-D computed tomography (CT) of the lung.

Eight anesthetized pigs underwent prospectively gated multidetector computed tomography using 2 devices: a charge-coupled device (CCD) camera and a laser sensor. The output signal of both gating devices was connected to the scanner instead of ECG unit. Inspiratory and expiratory images were obtained during "free-breathing" and analyzed in MPR mode for sharpness of bronchi, diaphragm and lung using a 4-point-score (1, excellent to 4, severe artifacts).

The CCD camera worked in all animals. Using the laser sensor, only 50% of expiratory scans could be acquired. All acquired images showed excellent sharpness (CCD camera vs. laser sensor) for trachea (1.1 +/- 0.3 vs. 1.3 +/- 0.5), bronchi (1.4 +/- 0.7 vs. 1.8 +/- 0.6), lung fissures (1.0 vs. 1.1 +/- 0.3), and lung parenchyma (1.0 +/- 0.2 vs. 1.4 +/- 0.6), and minor to major artifacts for diaphragm (1.5 +/- 0.8 vs. 2.0 +/- 1.0, P < 0.05) and pericardial lung structures (1.9 +/- 0.7 vs. 2.3 +/- 0.5).

High image quality for inspiratory and expiratory scans was achieved by free-breathing 3-D CT of the lung using noncontact prospective respiratory gating.