Related Experiment Video

Updated: Aug 9, 2026

Methylated DNA Immunoprecipitation
21:24

Methylated DNA Immunoprecipitation

Published on: January 2, 2009

[Epigenetics and cancer]

Guillaume J P Filion1, Pierre-Antoine Defossez

  • 1CNRS UMR218, Institut Curie, Section Recherche, 26 rue d'Ulm, 75248 Paris Cedex 05.

Bulletin Du Cancer
|April 22, 2006
PubMed

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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