Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anorectal dysfunction in multiple sclerosis.

E Munteis1, M Andreu, M J Téllez

  • 1Servei de Neurología, Hospital del Mar, Barcelona, Spain. 91774@imas.imim.es

Multiple Sclerosis (Houndmills, Basingstoke, England)
|April 25, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute myocarditis secondary to prostatitis following water vapour thermal therapy for benign prostatic hyperplasia: Presentation of two cases.

Radiologia·2026
Same author

Efficacy of cognitive rehabilitation in cognition and brain networks: A randomised clinical trial in patients with multiple sclerosis.

NeuroImage. Clinical·2025
Same author

Factors influencing recovery in a pediatric sample with disorders of consciousness: insights from an observational study.

Brain injury·2024
Same author

[Clinical profile and non-recreational methamphetamine abuse (shabu) among stroke patients in the Philippine population].

Revista de neurologia·2023
Same author

Lipidomic signature of stroke recurrence after transient ischemic attack.

Scientific reports·2023
Same author

Spontaneous pulmonary hematoma in patients with COVID-19.

Radiologia·2023
Same journal

UK consensus on pregnancy in multiple sclerosis: An update to 'Association of British Neurologists' guidance.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Comparative effectiveness of rituximab versus ocrelizumab in relapsing multiple sclerosis on clinical relapses and radiological outcomes in British Columbia, Canada.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Invisible symptoms in multiple sclerosis and their impact on social role participation: A multidimensional analysis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Interaction between smoking and <i>HLA-A*02:01</i> in multiple sclerosis progression.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Impact of multiple sclerosis disease-modifying therapies on chronic lesion tissue expansion.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Tobacco smoking disrupts bile acid and tryptophan metabolism in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
See all related articles

Anorectal dysfunction (ARD) affects nearly half of multiple sclerosis (MS) patients, often alongside urinary dysfunction (UD). Female sex, disease severity (EDSS), and UD predict ARD in MS.

Area of Science:

  • Neurology
  • Gastroenterology
  • Urology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease impacting the central nervous system.
  • Anorectal dysfunction (ARD) and urinary dysfunction (UD) are common but often underreported symptoms in MS patients.
  • Understanding the prevalence and predictors of ARD is crucial for improving patient quality of life.

Purpose of the Study:

  • To determine the frequency of anorectal dysfunction (ARD) in individuals with multiple sclerosis (MS).
  • To investigate the relationship between ARD and various clinical characteristics of MS.
  • To identify independent predictors of ARD in the MS population.

Main Methods:

  • A prospective transversal study was conducted with 193 patients diagnosed with multiple sclerosis (MS).

Related Experiment Videos

  • Data collected included demographic variables, MS clinical characteristics, and the presence of anorectal dysfunction (ARD) and urinary dysfunction (UD).
  • Statistical analyses, including univariate and logistic regression, were employed to identify associations and predictors.

    • Main Results:

    • Anorectal dysfunction (ARD) was identified in 48.2% of the 193 MS patients; urinary dysfunction (UD) was present in 50.2%.
    • ARD was significantly associated with older age, greater MS-related disability (EDSS), longer disease duration, and the presence of UD.
    • ARD was more prevalent in progressive forms of MS, and logistic regression identified female sex, EDSS, and UD as independent predictors.

    Conclusions:

    • Anorectal dysfunction (ARD) is a highly prevalent condition among patients with multiple sclerosis (MS).
    • Female sex, higher Expanded Disability Status Scale (EDSS) scores, and concurrent urinary dysfunction (UD) are significant independent predictors for the development of ARD in MS.
    • These findings highlight the need for routine screening and management of ARD in MS patients.