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Lichenoid and granulomatous stomatitis: an entity or a non-specific inflammatory process?
C Max Robinson1, Jon D Oxley, Justin Weir
1Department of Oral and Dental Science, University of Bristol, Bristol, UK. max.robinson@bristol.ac.uk
Summary
This study describes a rare oral condition, lichenoid and granulomatous stomatitis, affecting the upper lip. The persistent lesions were unresponsive to steroids but did not indicate systemic disease.
Area of Science:
- Oral pathology
- Dermatopathology
- Inflammatory diseases
Background:
- Oral mucosal biopsies commonly show lichenoid or granulomatous inflammation.
- Co-occurrence of both inflammatory patterns in a single biopsy is rare.
Purpose of the Study:
- To describe the clinico-pathological features of oral lesions with combined lichenoid and granulomatous inflammation.
- To propose a designation for this uncommon oral condition.
Main Methods:
- Clinico-pathological study of six patients.
- Microscopic examination of oral mucosal biopsies.
Main Results:
- All patients presented with similar upper lip mucosal lesions.
- Lesions exhibited both lichenoid and granulomatous inflammation.
- Lesions were persistent, steroid-refractory, localized, and not associated with systemic disease or neoplasia.
Conclusions:
- Proposed designation: 'lichenoid and granulomatous stomatitis'.
- Clinical and pathological findings suggest a possible unusual drug eruption in some cases.