Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amblyopia.

Jonathan M Holmes1, Michael P Clarke

  • 1Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. holmes.jonathan@mayo.edu

Lancet (London, England)
|April 25, 2006
PubMed
Summary
This summary is machine-generated.

Recent amblyopia trials suggest school entry screening and age-appropriate tests. Treatment focuses on children outside typical ranges, correcting refractive errors first, with informed choices between shorter patching or atropine regimens.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Initial postoperative alignment versus long-term outcomes in intermittent exotropia surgery.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2026
Same author

Testability and test-retest reliability of SpotChecks Contrast Sensitivity Test in children with unilateral amblyopia.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same author

Artificial intelligence for detection and staging of Alzheimer's disease using retinal images.

The Cochrane database of systematic reviews·2026
Same author

Web-Based Amblyopia Decision Support Tool.

JAMA ophthalmology·2026
Same author

At-home visual acuity in children using a custom iPhone application compared with standardized in-office visual acuity testing.

Optometry and vision science : official publication of the American Academy of Optometry·2026
Same author

Author Response: On the Limited Predictive Value of Prior Myopia Progression: Methodological Considerations for Clinical Prediction.

Investigative ophthalmology & visual science·2026
Same journal

Convergence of metabolic risk in obesity and normal BMI: does risk disappear?

Lancet (London, England)·2026
Same journal

Metabolic traits in obesity and normal BMI in industrialised countries: a multi-country analysis of national population-based studies.

Lancet (London, England)·2026
Same journal

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

Lancet (London, England)·2026
Same journal

The US Ebola response and the future of global health leadership.

Lancet (London, England)·2026
Same journal

Daniel Mason: a tale of change.

Lancet (London, England)·2026
Same journal

The 2026 Wakley-Wu Lien Teh Prize Essay: why medicine, and why stay?

Lancet (London, England)·2026
See all related articles

Area of Science:

  • Ophthalmology
  • Pediatric Medicine
  • Clinical Trials

Background:

  • Amblyopia, or 'lazy eye,' is a leading cause of visual impairment in children.
  • Current screening and treatment protocols for amblyopia are based on evolving clinical evidence.

Purpose of the Study:

  • To update recommendations for amblyopia screening and treatment based on recent randomized clinical trials.
  • To provide guidance on optimal timing, methods, and therapeutic choices for amblyopia management.

Main Methods:

  • Review of recent randomized clinical trials concerning amblyopia screening and treatment.
  • Analysis of evidence regarding screening timing, acuity testing, refractive error correction, and therapeutic interventions (patching, atropine).

Main Results:

Related Experiment Videos

  • School entry is identified as a potentially optimal time for a single amblyopia screening session.
  • Age-appropriate LogMAR acuity tests are recommended for screening.
  • Treatment is advised for children significantly outside age-expected visual acuity ranges, following refractive error correction.
  • Informed choices between reduced-duration patching (1-2 hours/day) or atropine drops (twice weekly) are suggested.

Conclusions:

  • Evidence supports revising amblyopia screening and treatment strategies.
  • Early and targeted interventions, with patient-centered choices, can be effective.
  • Less intensive initial therapeutic regimens may suffice for successful amblyopia management.