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Enzymatic biosensors.

Jeffrey D Newman1, Steven J Setford

  • 1Institute of BioScience and Technology, Cranfield University, Silsoe, Bedfordshire MK45 4DT, United Kingdom. j.d.newman@cranfield.ac.uk

Molecular Biotechnology
|April 25, 2006
PubMed
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The enzyme biosensor field, pioneered in 1962, is now dominated by glucose biosensors for diabetes management. This review examines the commercial growth, current status, and future trends in enzyme biosensor technology.

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Biotechnology

Background:

  • The biosensor field originated with Leland C. Clark, Jr.'s foundational work in 1962.
  • The market is currently led by glucose biosensors, crucial for diabetes self-management.
  • Enzyme electrodes represent a significant commercial success within biosensor technology.

Purpose of the Study:

  • To provide a historical overview of the enzyme biosensor field from a commercial perspective.
  • To evaluate the present state of enzyme biosensor technology.
  • To anticipate future developments and trends in this rapidly evolving area.

Main Methods:

  • Historical analysis of commercial development in the enzyme biosensor market.
  • Review of current technological status and market penetration.

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  • Trend analysis and future projection based on industry growth.

    • Main Results:

    • The enzyme biosensor field has experienced substantial commercial growth since its inception.
    • Glucose biosensors are the dominant product, enabling widespread diabetes self-monitoring.
    • The technology continues to advance, indicating a dynamic market landscape.

    Conclusions:

    • The commercial trajectory of enzyme biosensors highlights their significant impact on healthcare, particularly diabetes management.
    • Continued innovation is expected to drive further growth and diversification within the biosensor market.
    • Understanding historical commercialization is key to predicting future trends in biosensor development.