Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas

Donnie R Stacy1, Kim Ely, Pierre P Massion

  • 1Department of Radiation Oncology, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee 37232, USA.

Head & Neck
|April 26, 2006
PubMed
Summary

Nuclear factor E2 p45-related factor 2 (Nrf2) may serve as a biomarker for head and neck squamous cell carcinoma (HNSCC). Increased Nrf2 expression was observed in most HNSCC tumors, suggesting its potential for early disease detection.

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