Related Experiment Video
Updated: Aug 9, 2026

07:33
Quantification of Acanthamoeba spp. Motility
Published on: September 20, 2024
[Pathogenic free-living amoebic keratitis in China]
1Beijing Institute of Ophthalmology, Beijing Tongren Ophthalmic Center, Capital University of Medical Sciences, Beijing 100005, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|April 28, 2006
Summary
Acanthamoebic keratitis, a serious eye infection, has been extensively researched in China since 1992. Studies cover its causes, pathogen biology, diagnosis, and management to protect vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Context:
- The first reported case of acanthamoebic keratitis in China was in 1992.
- Over the last decade, significant research has focused on this vision-threatening condition.
Purpose:
- To comprehensively review and synthesize research on acanthamoebic keratitis in China.
- To highlight advancements in understanding and managing this ocular infection.
Summary:
- Research has explored the etiology, pathogen biology, and specimen handling of acanthamoeba.
- Studies have investigated pathogenesis, virulence factors, and animal models for acanthamoebic keratitis.
- Clinical diagnosis, pathology, immunology, and management strategies have been extensively studied.
Impact:
- Increased understanding of acanthamoebic keratitis in the Chinese population.
- Improved diagnostic and therapeutic approaches for this sight-threatening infection.
- Foundation for future research and clinical practice in managing acanthamoebic keratitis.
Related Concept Videos
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...