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Published on: July 4, 2017
Skeletal changes after experimentally displaced condylar process fracture in growing rats
Vanessa C B Teixeira1, Antonio C B Teixeira, João Gualberto C Luz
1Department of Oral and Maxillofacial Surgery, University of São Paulo, São Paulo, Brazil.
Summary
Mandibular condyle fractures in young rats caused degenerative changes and asymmetry in the mandible and maxilla. This study highlights the impact of condylar process fractures on facial skeletal development.
Area of Science:
- Oral and Maxillofacial Surgery
- Developmental Biology
- Skeletal Biology
Background:
- Mandibular condyle fractures are common injuries.
- Growth disturbances following condylar fractures in young individuals are a concern.
- Limited experimental data exists on the skeletal consequences of condylar fractures during development.
Purpose of the Study:
- To analyze skeletal changes following mandibular condyle fractures in a growing rat model.
- To investigate the long-term effects of condylar process injury on mandibular and maxillary development.
Main Methods:
- Unilateral fracture dislocations of the condylar process were surgically induced in young Wistar rats.
- A sham-operated group served as controls.
- Mandibular morphology was assessed via radiography and cephalometric analysis at 3 months of age.
Main Results:
- Fractured condylar processes exhibited atrophy and degenerative changes.
- Significant differences were observed in mandibular body height between experimental and control groups.
- Maxillary development, both anterior and posterior, was affected, indicating asymmetry.
Conclusions:
- Experimental mandibular condyle fractures during the growing period induce condylar degeneration.
- These fractures lead to mandibular asymmetry, impacting body height.
- Consequences extend to the maxilla, suggesting broader craniofacial developmental disruption.
