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Published on: March 7, 2017
Pontine atypical neurocytoma: case report
Bradley M Swinson1, William A Friedman, Anthony T Yachnis
1Department of Neurosurgery, University of Florida, Gainesville 32610, USA.
Neurosurgery
|April 28, 2006
Summary
Extraventricular neurocytomas are rare, with pontine neurocytoma being exceptionally uncommon. This case highlights successful management of a pontine neurocytoma, achieving a symptom-free outcome with no recurrence post-surgery.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Neuropathology
Background:
- Neurocytomas typically arise within the supratentorial ventricular system.
- Extraventricular neurocytomas are exceedingly rare, with pontine location being exceptionally uncommon.
- This report details the second documented case of a pontine neurocytoma.
Observation:
- A 58-year-old male presented with a 4-month history of headache and unilateral paresthesia.
- Magnetic resonance imaging revealed a 2.6 x 2.2 cm ring-enhancing cystic mass in the right pons.
- MRI-guided stereotactic biopsy diagnosed an atypical neurocytoma.
Findings:
- The patient received external beam radiation therapy followed by temozolomide chemotherapy due to tumor progression.
- Despite initial treatments, symptoms worsened, necessitating aggressive subtotal tumor resection via suboccipital craniectomy.
- Postoperatively, the patient achieved a symptom-free status with no evidence of residual or recurrent tumor on MRI scans at 28 months.
Implications:
- This case underscores the importance of considering rare tumor locations and histological subtypes in neuro-oncology.
- Successful surgical resection can lead to favorable outcomes even in challenging locations like the pons.
- Further research into optimal treatment strategies for extraventricular neurocytomas is warranted.
