Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an expressed GABAA receptor

Allosteric modulators of the δ GABAA receptor subtype demonstrate a therapeutic effect in morphine-antinociceptive tolerance and withdrawal in mice.

Neuropharmacology·2022

Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effects.

The AAPS journal·2009

Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C.

AAPS pharmSci·2001

Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.

Psychopharmacology·2001

Predicting the impact of physiological and biochemical processes on oral drug bioavailability.

Advanced drug delivery reviews·2001

Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid.

Psychopharmacology·2001

Comparative Effects of Quercetin and its α- and β-D-glucoside Derivatives in LPS-Stimulated C6 Astroglial Cells.

Neurochemical research·2026

The Mechanism of Long Non-coding RNA GABPB1-AS1/SLC12A5 Regulating Neuronal Ferroptosis in Epileptic Seizures.

Neurochemical research·2026

Study on the Expression of MiR-642b-3p in Spontaneous Intracerebral Hemorrhage and Its Regulatory Mechanism on Endothelial Cell Injury.

Neurochemical research·2026

Atorvastatin Exerts Context-Dependent Metabolic and Beneficial Effects on Behavior and Apoptotic Signaling in a Cafeteria Diet-Induced Metabolic Dysfunction Model.

Neurochemical research·2026

Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Alleviate Age-Related Insomnia in Rats by Suppressing Neuronal Ferroptosis in the Hippocampal Dentate Gyrus.

Neurochemical research·2026

The Potential of Cannabidiol for the Treatment of Psychosis: Endocannabinoid Regulation of Serotonergic Neurotransmission via Serotonin 5-HT1A/2A Receptors.

Neurochemical research·2026

Chitosan microparticle-based antibacterial nasal barrier formulation and in vivo evaluations.

Turkish journal of chemistry·2026

Bioactive compound ginkgolide B alleviates food allergy by regulating mTOR signaling pathway.

Frontiers in immunology·2026

Post-Crosslinked Hydrazidine-Functionalized Resorcinol-Formaldehyde Imprinted Polymer for Selective S-Ketorolac Recognition.

Chirality·2026

Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition.

Journal of medicinal chemistry·2026

Convergent Synthesis of a Bifunctional GPI as a Universal Platform to Access Diverse GPI and GPI-Anchored Protein Probes.

Organic letters·2026

Regio- and Stereoselective Synthesis of Deuterium-Labeled Glutamic Acids via a Tetramic Acid Derivative.

The Journal of organic chemistry·2026

Related Experiment Videos

Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an

Related Concept Videos

Allosteric modulators of the δ GABAA receptor subtype demonstrate a therapeutic effect in morphine-antinociceptive tolerance and withdrawal in mice.

Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effects.

Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C.

Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors.

Predicting the impact of physiological and biochemical processes on oral drug bioavailability.

Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid.

Comparative Effects of Quercetin and its α- and β-D-glucoside Derivatives in LPS-Stimulated C6 Astroglial Cells.

The Mechanism of Long Non-coding RNA GABPB1-AS1/SLC12A5 Regulating Neuronal Ferroptosis in Epileptic Seizures.

Study on the Expression of MiR-642b-3p in Spontaneous Intracerebral Hemorrhage and Its Regulatory Mechanism on Endothelial Cell Injury.

Atorvastatin Exerts Context-Dependent Metabolic and Beneficial Effects on Behavior and Apoptotic Signaling in a Cafeteria Diet-Induced Metabolic Dysfunction Model.

Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Alleviate Age-Related Insomnia in Rats by Suppressing Neuronal Ferroptosis in the Hippocampal Dentate Gyrus.

The Potential of Cannabidiol for the Treatment of Psychosis: Endocannabinoid Regulation of Serotonergic Neurotransmission via Serotonin 5-HT1A/2A Receptors.

Chitosan microparticle-based antibacterial nasal barrier formulation and in vivo evaluations.

Bioactive compound ginkgolide B alleviates food allergy by regulating mTOR signaling pathway.

Post-Crosslinked Hydrazidine-Functionalized Resorcinol-Formaldehyde Imprinted Polymer for Selective S-Ketorolac Recognition.

Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition.

Convergent Synthesis of a Bifunctional GPI as a Universal Platform to Access Diverse GPI and GPI-Anchored Protein Probes.

Regio- and Stereoselective Synthesis of Deuterium-Labeled Glutamic Acids via a Tetramic Acid Derivative.

Related Experiment Videos

Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an...

Related Concept Videos

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Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an