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Cytokine gene polymorphism in human disease: on-line databases, Supplement 3
1NANEA at Department of Epidemiology, Institute of Public Health, University of Aarhus, Denmark. mvh@ssi.dk
Genes and Immunity
|April 28, 2006
Summary
This study details positive associations between cytokine single nucleotide polymorphisms (SNPs) and human diseases, based on research from 2002-2005. A downloadable file lists these cytokine SNPs and their disease or expression pattern links.
Area of Science:
- Immunogenetics
- Human Genetics
- Molecular Biology
Background:
- The role of cytokine single nucleotide polymorphisms (SNPs) in human diseases is gaining significant attention.
- Previous research has established a growing interest in understanding the functional impact of these genetic variations.
Purpose of the Study:
- To document and summarize positive associations between cytokine SNPs and human diseases.
- To update the Cytokine Gene Polymorphism in Human Disease: On-line database with findings from 2002-2005.
Main Methods:
- Systematic review of scientific literature published between 2002 and 2005.
- Data compilation of cytokine SNPs and their reported associations with human diseases or expression patterns.
Main Results:
- Identified and cataloged numerous positive associations between specific cytokine SNPs and various human diseases.
- Compiled a comprehensive list of investigated SNPs and their corresponding disease or expression pattern associations.
Conclusions:
- The findings highlight the increasing evidence linking cytokine genetic variations to disease susceptibility and progression.
- The updated database serves as a valuable resource for researchers investigating the genetic basis of human diseases.
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