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Updated: Aug 9, 2026
04:28
Evaluation of Blood Lactate and Plasma Insulin During High-intensity Exercise by Antecubital Vein Catheterization
Published on: May 18, 2018
Local and systemic effects on blood lactate concentration during exercise with small and large muscle groups
R Chudalla1, S Baerwalde, G Schneider
1Sports and Exercise Physiology, Medical School Hannover, Carl-Neubergstrasse 1, 30625 Hannover, Germany.
Pflugers Archiv : European Journal of Physiology
|April 28, 2006
Summary
Lactate release during moderate exercise increases arterial lactate levels when combined with forearm exercise. Norepinephrine influences this release, but not epinephrine or oxygen levels.
Area of Science:
- Exercise Physiology
- Human Physiology
- Biochemistry
Background:
- Lactate production during exercise is a key metabolic marker.
- Understanding factors influencing lactate release is crucial for exercise science.
Purpose of the Study:
- To examine the relationship between arterial lactate concentration and lactate release.
- To investigate the impact of catecholamines on lactate release during exercise.
Main Methods:
- 14 healthy men performed forearm exercise and superimposed cycling at 65% maximal power.
- Measurements included arterial lactate concentration ([lac](art)) and venous lactate concentration ([lac](ven)).
- Correlation analysis was performed for lactate, oxygen tension (P(v)O(2)), norepinephrine ([NE]), and epinephrine ([EPI]).
Main Results:
- Venous lactate increased with forearm exercise alone, while arterial lactate remained stable.
- Combined exercise (forearm + cycling) elevated both arterial and venous lactate.
- A significant correlation was found between arterial lactate and norepinephrine ([NE]).
- No significant correlation was detected between lactate release and epinephrine ([EPI]) or oxygen tension (P(v)O(2)).
Conclusions:
- Lactate release from muscles during moderate exercise is not solely dependent on oxygen availability.
- Norepinephrine plays a role in modulating lactate release during combined exercise.
- Epinephrine does not appear to influence lactate release at moderate exercise intensities.
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