Pyrimidinyl nitronyl nitroxides
Peter Brough1, Jacques Pécaut, André Rassat
1CEA-Grenoble, Département de Recherche Fondamentale sur la Matière Condensée, Service de Chimie Inorganique et Biologique,UMR-E3, CEA-UJF, 17 rue des Martyrs, 38054 Grenoble Cedex 09, France.
Abstract:
The chemistry of 2,2,4,4-substituted pentane derivatives has been investigated with the aim of providing a flexible and versatile synthetic route to pyrimidinyl nitronyl nitroxides, in which the bis-N-oxy fragment is incorporated in a six-membered ring. The synthesis of 2,4-diamino-2,4-dimethylpentane and 2,4-bis(hydroxylamino)-2,4-dimethylpentane, convenient precursors of these nitroxides, is described and full characterization of a series of pyrimidinyl nitronyl nitroxides is reported, along with a preliminary study of their coordination properties.
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