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Updated: Aug 9, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
[Aging and age-related macular degeneration]
1Department of Ophthalmology, Keck School of Medicine at University of Southern California, Los Angeles, CA 90033, USA. shikunhe@usc.edu
Abstract:
Aging is a common feature of biological changes in the eye, especially in the retina. It is recognized that the pathogenesis of age-related macular degeneration (AMD) involves changes of RPE-Bruch membrane and choroid capillaries complex, which includes function and structure abnormal in the complex accompanied with aging processes. Aging may be an important event to contribute to the pathogenesis of AMD, but aging dose not directly led to the occurrence of AMD, multifactor is involved in the initiation of the pathogenesis of AMD. Therefore, this review is summarizing the latest concepts of the rale of aging in the occurrence of AMD.
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