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HIV and aging.

Sanjiv Shah1, Donna Mildvan

  • 1Division of Infectious Diseases, Department of Medicine, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, USA. sshah2@nshs.edu

Current Infectious Disease Reports
|April 29, 2006
PubMed
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The number of older adults living with HIV is growing, with many diagnosed late. Early HIV diagnosis and treatment are crucial for this aging population.

Area of Science:

  • Geriatrics
  • Infectious Diseases
  • Public Health

Background:

  • An increasing proportion of individuals living with HIV in the US are aged 50 and older.
  • Stable HIV incidence and effective antiretroviral therapy contribute to this demographic shift.
  • Older adults diagnosed with HIV are more likely to present with AIDS compared to younger individuals.

Purpose of the Study:

  • To highlight the growing prevalence of HIV in older adults.
  • To emphasize the need for increased clinical suspicion of HIV in geriatric populations.
  • To discuss challenges and considerations for managing HIV in older individuals.

Main Methods:

  • Review of current epidemiological data on HIV in older adults.
  • Analysis of treatment outcomes and challenges in this demographic.

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  • Discussion of clinical implications for diagnosis, treatment, and prevention.

    • Main Results:

    • Older adults with HIV are disproportionately diagnosed with AIDS.
    • Immunologic recovery may be less robust in older individuals on antiretroviral therapy compared to younger counterparts.
    • Virologic suppression rates are comparable between younger and older treatment-naïve patients.

    Conclusions:

    • Clinicians must consider HIV in older persons to prevent diagnostic delays.
    • Co-morbidities and polypharmacy in older adults complicate HIV management.
    • HIV prevention strategies must include discussions of sexual risk with older patients.