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Risk factors for developing sleep-disordered breathing in patients with recent ischaemic stroke
A T Noradina1, B B Hamidon, H Roslan
1Department of Medicine, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff Bandar Tun Razak, Cheras, Kuala Lumpur. noradinatajudin2000@yahoo.com
Singapore Medical Journal
|April 29, 2006
Summary
Sleep-disordered breathing (SDB) is highly prevalent in recent ischemic stroke patients. Diabetes and smoking are key predictors of SDB after stroke.
Area of Science:
- Neurology
- Sleep Medicine
- Cardiovascular Research
Background:
- Sleep-disordered breathing (SDB) is frequently observed in ischemic stroke patients, with prevalence rates ranging from 43% to 72% based on an apnea-hypopnea index (AHI) of 10 or higher.
- Existing research indicates a link between SDB and cardiovascular complications, highlighting the importance of further investigation in stroke populations.
Purpose of the Study:
- To determine the frequency of SDB in recent ischemic stroke patients admitted to Hospital Universiti Kebangsaan Malaysia (HUKM).
- To investigate the relationship between SDB and known risk factors for ischemic stroke.
Main Methods:
- A cross-sectional, prospective study was conducted with 28 consecutive acute ischemic stroke patients.
- Sleep studies were performed within one to four weeks post-stroke onset.
- Demographic data and associated risk factors were collected and analyzed.
Main Results:
- The prevalence of SDB varied by AHI cut-off: 92.8% (AHI ≥ 5), 78.5% (AHI ≥ 10), 44.5% (AHI ≥ 15), and 37.7% (AHI ≥ 20).
- Diabetes mellitus and a history of smoking were identified as significant predictors of SDB (AHI ≥ 15) in recent ischemic stroke patients.
Conclusions:
- A high prevalence of SDB was confirmed in recent ischemic stroke patients at HUKM, consistent with other studies.
- Diabetes mellitus and smoking history are strong predictors for the development of SDB following an ischemic stroke.
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