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Possible interaction between HLA-DRbeta1 and thyroglobulin variants in Graves' disease

Susan E Hodge1, Yoshiyuki Ban, Lisa J Strug

  • 1Division of Clinical-Genetic Epidemiology, New York State Psychiatric Institute, New York, New York.

Thyroid : Official Journal of the American Thyroid Association
|May 2, 2006
PubMed
Summary

Graves' disease (GD) risk may be influenced by an interaction between specific HLA-DR and thyroglobulin (Tg) gene variants. The study suggests the R- genotype and CC genotype may work together to increase susceptibility to GD.

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