Management of primary herpetic gingivostomatitis in young children

Howard Faden1

  • 1Department of Pediatrics, School of Medicine, State University of New York at Buffalo, Women and Children's Hospital of Buffalo, Buffalo, NY 14222, USA. hfaden@upa.chob.edu

Insights

Treatment for primary herpetic gingivostomatitis in children often involved topical agents like Maalox/diphenhydramine or viscous lidocaine. Acyclovir was underutilized, and topical agent administration was frequently problematic.

Area of Science:

  • Pediatric infectious diseases
  • Oral medicine

Background:

  • Primary herpetic gingivostomatitis is a common viral infection in children.
  • Effective symptom management is crucial for patient comfort and recovery.

Observation:

  • A retrospective chart review identified 48 cases of primary herpetic gingivostomatitis treated between 1999 and 2003.
  • Patients ranged from 8 months to 12 years old, with a median age of 2 years 7 months.

Findings:

  • All patients received fluids and analgesics.
  • Topical therapies included Maalox/diphenhydramine (73%), viscous lidocaine (15%), and acyclovir (17%).
  • Eleven patients received multiple topical treatments, and administration methods/dosing for topical agents were often inconsistent.

Implications:

  • Current treatment protocols for primary herpetic gingivostomatitis may not be optimal.
  • There is a need for standardized guidelines for topical agent administration.
  • Increased utilization of acyclovir may be beneficial.
Abstract

Related Concept Videos

Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...