Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development and multiplexed control of latching pneumatic valves using microfluidic logical structures.

William H Grover1, Robin H C Ivester, Erik C Jensen

  • 1Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Lab on a Chip
|May 3, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disintegration Fingerprinting: A Low-Cost and User-Friendly Tool for Identifying Substandard and Falsified Solid-Dosage Medicines.

Analytical chemistry·2026
Same author

Microfabricated Onsite Analyzer for Biomarkers (MOAB) for Automated Crew Health Monitoring.

ACS sensors·2025
Same author

Wild Foundress Queen Bumble Bees Make Numerous, Short Foraging Trips and Exhibit Frequent Nest Failure: Insights From Trap-Nesting and RFID Tracking.

Ecology and evolution·2025
Same author

Controlling Biomedical Devices Using Pneumatic Logic.

Annals of biomedical engineering·2024
Same author

Integrated high performance microfluidic organic analysis instrument for planetary and space exploration.

Lab on a chip·2024
Same author

Poly(dimethylsiloxane) as a room-temperature solid solvent for photophysics and photochemistry.

Physical chemistry chemical physics : PCCP·2024
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Novel microfluidic valves use pneumatic control for latching, enabling independent operation. These compact, low-power valves reduce system complexity and costs for microfluidic devices.

Area of Science:

  • Microfluidics
  • Pneumatic systems
  • MEMS (Micro-Electro-Mechanical Systems)

Background:

  • Microfluidic devices often require complex control systems for fluid manipulation.
  • Existing microfluidic valves can be bulky, power-hungry, and expensive.
  • Need for miniaturized, efficient, and cost-effective valve solutions in microfluidics.

Purpose of the Study:

  • To develop and characterize novel latching microfluidic valve structures.
  • To demonstrate independent control of these valves using an on-chip pneumatic demultiplexer.
  • To reduce the size, power consumption, and cost of microfluidic analysis devices.

Main Methods:

  • Development of normally-closed pneumatic monolithic membrane valves.
  • Integration of these valves into three- and four-valve latching circuits.

Related Experiment Videos

  • Demonstration of an on-chip demultiplexer for controlling multiple independent valves with minimal inputs.

    • Main Results:

    • Latching microfluidic valves were successfully developed and characterized.
    • Short vacuum or pressure pulses (120 ms) were sufficient to maintain valve states for minutes.
    • An on-chip demultiplexer controlled 2(n-1) independent latching valves using n pneumatic inputs.

    Conclusions:

    • The developed latching valves offer efficient, long-term state holding.
    • The on-chip demultiplexer significantly reduces the number of required pneumatic inputs.
    • These pneumatic valve structures can be integrated into complex microfluidic systems, analogous to electronic logic gates, enabling miniaturization and cost reduction.