[Kinetic methods of reverse mechanism functions of receptor domain Na+- and K+-channels]

Complete kinetic diagrams of the gate mechanisms of Na(+)- and K(+)-channels of receptor domains were examined. Analysis of various states of gate mechanisms of these channels allow to reveal the fundamental characteristics of Na(+)- and K(+)-channels of receptor domains which can underlie the molecular mechanisms of a number of processes dealing with the functioning of receptor domains. Taking into account these characteristics of Na(+)- and K(+)-channels of receptor domains, the molecular mechanisms of generation and spreading of the action potential and the molecular mechanisms of synaptic transmission, in chemical, and electrical synapses, was proposed. A possible role of receptor domains in the processes of cell differentiation, proliferation and carcinogenesis are also discussed.