Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Macroglossia].

P G C J van Dijk1, C M Suttorp, I van der Waal

  • 1Uit de Afdeling Mondziekten en Kaakchirurgie/Pathologie van het VU Medisch Centrum in Amsterdam.

Nederlands Tijdschrift Voor Tandheelkunde
|May 4, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immediate Orthodontic Repositioning of Traumatically Extruded Incisors in a Patient With Cleft Lip and Alveolus: A Case Report.

Case reports in dentistry·2026
Same author

Incisal Interference Correction after Severe Extrusive Luxation Trauma during Orthodontic Treatment.

Case reports in dentistry·2022
Same author

The role of the dentist in the diagnosis and management of patients with oral mucosal diseases.

Medicina oral, patologia oral y cirugia bucal·2021
Same author

Professional diagnostic delay in osteosarcomas of the jaws.

Medicina oral, patologia oral y cirugia bucal·2020
Same author

Oral leukoplakia; a proposal for simplification and consistency of the clinical classification and terminology.

Medicina oral, patologia oral y cirugia bucal·2019
Same author

Knowledge about oral leukoplakia for use at different levels of expertise, including patients.

Oral diseases·2018
Same journal

[Indications for and claims to dental specialties: regulatory framework].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Justification and optimization of intraoral and panoramic radiographs in oral care].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[A new era in acute dental care: organizational changes and legal implications].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Diabetes mellitus: new insights and developments].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Soft tissue injuries of the face; a summary with practical guidelines].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Digital analysis of occlusion and articulation using the T-Scan: the scientific background].

Nederlands tijdschrift voor tandheelkunde·2026
See all related articles

A patient with multiple myeloma (Kahler's disease) presented with tongue enlargement due to amyloid deposition. Despite stem cell transplantation, macroglossia persisted one year post-treatment.

Area of Science:

  • Oral and Maxillofacial Surgery
  • Hematology
  • Oncology

Background:

  • Amyloidosis, a condition involving abnormal protein deposits, can manifest in various organs, including the tongue.
  • Multiple myeloma (Kahler's disease) is a cancer of plasma cells that can lead to systemic amyloid deposition.

Observation:

  • A 63-year-old woman experienced progressive tongue enlargement (macroglossia).
  • Initial biopsy revealed amyloid deposition.
  • Subsequent investigations confirmed multiple myeloma and prior carpal tunnel syndrome likely due to amyloid.

Findings:

  • The patient underwent successful stem cell transplantation for multiple myeloma.
  • One-year follow-up showed no significant regression of macroglossia despite systemic treatment.

Related Experiment Videos

Implications:

  • This case highlights the persistent oral manifestations of amyloidosis secondary to multiple myeloma.
  • Effective systemic treatment may not always resolve established macroglossia.
  • Further research into managing amyloid-related macroglossia in multiple myeloma patients is warranted.