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Published on: November 4, 2010
Validation of a beta-agonist long-term asthma control scale derived from computerized pharmacy data.
Michael Schatz1, Robert S Zeiger, William M Vollmer
1Department of Allergy (San Diego), Kaiser-Permanente Medical Care Program, Kaiser-Permanente Medical Center, CA 92111, USA. michael.x.schatz@kp.org
The Journal of Allergy and Clinical Immunology
|May 6, 2006
Summary
A new asthma control scale using administrative data, based on short-acting beta-agonist canisters dispensed, effectively reflects symptom control. This scale identifies patients at risk for future asthma exacerbations and healthcare utilization.
Area of Science:
- Pulmonary Medicine
- Health Services Research
- Data Science in Healthcare
Background:
- Clinical assessment of asthma control relies on validated tools.
- No asthma control scale has been reported using administrative data.
Purpose of the Study:
- To validate a novel asthma control scale derived from administrative data.
- To assess the reliability of a beta-agonist dispensing scale for asthma control.
Main Methods:
- A 4-level asthma control scale was developed based on short-acting beta-agonist canisters dispensed in 12 months.
- Construct and predictive validity were assessed using surveys and linked pharmacy data from 2250 persistent asthma patients.
- Validated asthma symptom and control tools were used for comparison.
Main Results:
- The beta-agonist scale demonstrated significant construct validity, correlating with symptom control factors and validated scales (r = 0.31).
- Each increase in the beta-agonist scale level predicted higher risks of subsequent asthma hospitalizations, emergency visits, and oral corticosteroid use.
- These associations were independent of prior medication use.
Conclusions:
- An asthma control scale based on dispensed beta-agonist canisters from administrative data accurately reflects symptom control.
- This scale aids in identifying patients at risk for future acute asthma events.
- The scale supports population management and clinical interventions to prevent asthma morbidity.
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