Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional abdominal pain syndrome.

Ray E Clouse1, Emeran A Mayer, Qasim Aziz

  • 1Division of Gastroenterology, Washington University, St Louis, Missouri 63110, USA. rclouse@im.wustl.edu

Gastroenterology
|May 9, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From dysbiosis to malignancy: decoding gut-driven pathways to clinical management in hepatocellular carcinoma.

Frontiers in cellular and infection microbiology·2026
Same author

The DICA endoscopic score and the CODA clinical score may predict the severity of acute diverticulitis and the risk of hospitalisation: results from an international multicentre prospective cohort study.

Techniques in coloproctology·2026
Same author

Disorders of Gut-Brain Interaction and the Rome V Process.

Gastroenterology·2026
Same author

Gastrointestinal Symptoms and Systemic Comorbidities in Patients With POTS: A Systematic Review and Meta-Analysis.

Neurogastroenterology and motility·2026
Same author

Central and Peripheral Neuromodulators in Functional Dyspepsia and Gastroparesis: A Symptom-Based Clinical Review.

Neurogastroenterology and motility·2026
Same author

Centrally Mediated Disorders of Gastrointestinal Pain.

Gastroenterology·2026
Same journal

How important is fiber in the Crohn's disease story?

Gastroenterology·2026
Same journal

Reply to "Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy".

Gastroenterology·2026
Same journal

Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy.

Gastroenterology·2026
Same journal

A High-Risk Impaction: To Scope or to Stent First?

Gastroenterology·2026
Same journal

Epithelial FOXP3 Orchestrates O-Glycosylated IL6 Secretion to Drive Pancreatic Fibrocarcinogenesis.

Gastroenterology·2026
Same journal

Reply.

Gastroenterology·2026
See all related articles

Functional abdominal pain syndrome (FAPS) is a complex disorder distinct from other functional bowel issues, often linked to psychiatric conditions. Management involves physician-patient trust, targeted medications like antidepressants, and psychological therapies.

Area of Science:

  • Gastroenterology
  • Pain Medicine
  • Psychiatry

Background:

  • Functional abdominal pain syndrome (FAPS) is a distinct functional bowel disorder characterized by its lower prevalence and symptoms unrelated to food or defecation.
  • FAPS exhibits a higher comorbidity with psychiatric disorders, suggesting complex underlying mechanisms.
  • The etiology and pathophysiology of FAPS remain incompletely understood, potentially involving peripheral neuropathic pain or altered endogenous pain modulation.

Purpose of the Study:

  • To differentiate Functional abdominal pain syndrome (FAPS) from other functional bowel disorders.
  • To outline diagnostic criteria and management strategies for FAPS.
  • To explore potential pathophysiological mechanisms in FAPS.

Main Methods:

  • Diagnosis relies on positive symptom criteria and a history of symptoms, avoiding extensive evaluation in the absence of alarm signs.

Related Experiment Videos

  • Management strategies emphasize a strong physician-patient relationship and empirical treatment algorithms.
  • Treatment modalities include centrally acting drugs (antidepressants, anticonvulsants) and psychological therapies (psychotherapy, relaxation, hypnosis).

    • Main Results:

    • FAPS presents unique characteristics compared to other functional bowel disorders.
    • Diagnosis is primarily clinical, guided by symptom criteria.
    • Treatment is multimodal, incorporating pharmacotherapy and psychological interventions, with drug selection influenced by comorbidities.

    Conclusions:

    • Functional abdominal pain syndrome (FAPS) requires a distinct approach due to its unique clinical features and potential pathophysiological underpinnings.
    • Effective management hinges on a therapeutic alliance and tailored empirical treatments.
    • Multidisciplinary pain clinic approaches may benefit patients with refractory FAPS.