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Pathological review of melanotic neuroectodermal tumour of infancy in India

N C Aryya1, B L Rastogi, A N Gangopadhyay

  • 1Department of Pathology, Banaras Hindu University, Varanas.

Indian Journal of Pathology & Microbiology
|July 1, 1991
PubMed

Insights

Melanotic neuroectodermal tumour of infancy (MNETI) is a rare condition affecting infants, predominantly in the maxilla. This review highlights 14 Indian cases, noting male predilection and benign histological features.

Area of Science:

  • Pediatric Oncology
  • Oral Pathology
  • Dermatology

Background:

  • Melanotic neuroectodermal tumour of infancy (MNETI) is a rare, benign, pigmented tumor of infancy.
  • MNETI predominantly affects the maxilla in infants under one year old.
  • Literature review indicates a higher incidence in males.

Purpose of the Study:

  • To review and analyze reported cases of MNETI in India.
  • To describe the clinical and histological characteristics of MNETI in the Indian population.
  • To contribute to the understanding of MNETI epidemiology and presentation.

Main Methods:

  • Comprehensive literature search for MNETI cases in India.
  • Analysis of case reports focusing on patient demographics, tumor location, and histological findings.
  • Compilation and discussion of morphological features.

Main Results:

  • Fourteen cases of MNETI were identified in India.
  • All affected infants were under one year of age.
  • The majority of lesions were located in the maxilla, with one case in the orbit. Males were more frequently affected than females.
  • Histological examination revealed classical, benign tumor characteristics.

Conclusions:

  • MNETI in India mirrors global trends, predominantly affecting the maxilla in young male infants.
  • The benign and classical histological nature of these tumors is consistent.
  • Further research can help elucidate the etiology and optimal management of MNETI.

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