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Pleomorphic adenoma of the vulva: a review illustrated by a clinical case
R H M Dykgraaf1, M M S van Veen, E E C van Bekkum-de Jonge
1Division of Gynaecology and Gynaecologic Oncology, Department of Obstetrics and Gynaecology, Erasmus MC/Daniel den Hoed University Medical Center, Rotterdam, The Netherlands.
Abstract:
The pleomorphic adenoma of the vulva is an extremely scarce diagnosis. This form of neoplasm is more frequently observed in other topographic sites of the human body. Treatment modalities largely derive from experiences with the pleomorphic adenoma located in these other sites. As a result of similarity with other tumors and scarcity of the neoplasm, the diagnosis of pleomorphic adenoma of the vulva is easily missed in daily routine practice. Recurrences of this neoplasm are frequently observed with an estimated incidence of malignant transformation of 25%. Addressing this previously mentioned issue, an extensive surgical excision and long-term follow-up is advocated. This report is illustrated by the case of a 66-year-old woman who was admitted to our hospital with a pleomorphic adenoma of the vulva, diagnosed by pathologic assessments following surgical excision. As a result of the rarity of this diagnosis, characteristics and treatment of extravulvar in addition to vulvar localizations of the pleomorphic adenoma are reviewed.
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