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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

A pilot study with a new, rapid-exchange, thrombus-aspirating device in patients with thrombus-containing lesions:

Francesco Burzotta1, Carlo Trani, Enrico Romagnoli

  • 1Institute of Cardiology, Catholic University, Rome, Italy. f.burzotta@eudoramail.com

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|May 10, 2006
PubMed

Insights

A new thrombus-aspirating catheter effectively reduced clot burden and improved coronary blood flow in patients with acute coronary syndromes. This highlights the importance of aspiration in managing complex coronary lesions.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Research
  • Medical Device Technology

Background:

  • Distal embolization of thrombus contributes to myocardial no-reflow during percutaneous coronary intervention (PCI) in acute coronary syndromes (ACS).
  • Techniques reducing thrombus burden may enhance myocardial reperfusion post-PCI.

Purpose of the Study:

  • To evaluate the efficacy of the Diver C.E., a novel rapid-exchange thrombus-aspirating catheter.
  • To assess its performance in patients with thrombotic coronary lesions undergoing PCI.

Main Methods:

  • Prospective enrollment of 50 patients with acute myocardial infarction or non-ST-elevation ACS and coronary thrombus.
  • Utilized the Diver C.E. catheter for thrombus aspiration from the culprit lesion.
  • Assessed angiographic outcomes including coronary flow (TIMI score, cTFC), thrombus score (TS), and myocardial perfusion (MBG).

Main Results:

  • Successful thrombus aspiration in 96% of patients.
  • Significant reduction in thrombus burden (TS) and improvement in coronary flow (TIMI, cTFC).
  • Greater thrombus removal correlated with improved myocardial perfusion (MBG).

Conclusions:

  • The Diver C.E. is an effective, user-friendly device for reducing thrombus burden in coronary lesions.
  • Improved myocardial perfusion following aspiration underscores its value in managing thrombus-laden coronary arteries.
Abstract

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