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Published on: December 11, 2017
Risk factors for requirement of permanent pacemaker implantation after aortic valve replacement
Hasan Basri Erdogan1, Nihan Kayalar, Hasan Ardal
1Kosuyolu Heart and Research Hospital, Department of Cardiovascular Surgery, Istambul, Turkey.
Insights
Permanent pacemaker implantation is uncommon after aortic valve replacement (AVR). Key risk factors include annular calcification, bicuspid aortic valve, female sex, conduction blocks, hypertension, and longer perfusion times.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Aortic valve replacement (AVR) is a common procedure for aortic valve disease.
- Understanding the incidence and predictors of permanent pacemaker (PPM) requirement post-AVR is crucial for patient management.
Purpose of the Study:
- To determine the frequency of PPM implantation after AVR.
- To identify risk factors associated with the need for permanent pacing post-AVR.
Main Methods:
- Retrospective analysis of 465 patients undergoing AVR between 1994 and 2004.
- Evaluation of patient demographics, preoperative conditions, operative details, and outcomes related to permanent pacing.
Main Results:
- 19 patients (4.1%) required PPM implantation.
- Significant risk factors identified by multivariate analysis included female sex, annular calcification, bicuspid aortic valve, right or left bundle branch block, hypertension, and total perfusion time.
Conclusions:
- Irreversible atrioventricular block necessitating PPM is an infrequent complication of AVR.
- Risk factors such as annular calcification, bicuspid aortic valve, female sex, conduction abnormalities, hypertension, and prolonged perfusion time are associated with PPM requirement.
Background:
The aim of this study was to evaluate the frequency of requirement for permanent pacing and related risk factors after aortic valve replacement.
Methods:
Among 465 patients operated between 1994 and 2004, 19(4.1%) patients with a mean age 49.9 +/- 17.2 years required the implantation of a permanent pacemaker. Eleven of them were female (57.9%). The main indication was aortic stenosis (89.5%). Severe annular calcification was documented in 78.9% of them, and the aortic valve was bicuspid in 57.9%.
Results:
Risk factors for permanent pacing after aortic valve replacement (AVR) identified by univariate analysis were female sex, hypertension, preoperative ejection fraction, aortic stenosis, annular calcification, bicuspid aorta, presence of right bundle branch block (RBBB) or left bundle branch block (LBBB), prolonged aortic cross-clamp and perfusion times, and preoperative use of calcium channel blockers. Multivariate analysis showed that female sex (p = 0.01, OR; 5.21, 95% CI: 1.48-18.34), annular calcification (p < 0.001, OR; 0.05, 95% CI: 0.01-0.24), bicuspid aortic valve (p = 0.02, OR; 0.24, 95% CI: 0.07-0.84), presence of RBBB (p = 0.009, OR; 0.03, 95% CI: 0.003-0.44) or LBBB (p = 0.01, OR; 0.13, 95% CI: 0.02-0.69), hypertension (p = 0.03, OR; 0.22, 95%CI: 0.05-0.89), and total perfusion time (p = 0.002, OR; 1.05, 95% CI: 1.01-1.08) were associated risk factors.
Conclusion:
Irreversible atrioventricular block requiring a permanent pacemaker implantation is an uncommon complication after AVR. Risk factors are annular calcification, bicuspid aorta, female sex, presence of RBBB or LBBB, prolonged total perfusion time, and hypertension.
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