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Calciphylaxis associated with alcoholic cirrhosis
J R Ferreres1, J Marcoval, X Bordas
1Department of Dermatology, IDIBELL, Hospital Universitari de Bellvitge, Barcelona, Spain. 36660fjr@comb.es
Abstract:
Calciphylaxis is an uncommon disease characterized by calcification of dermal vessels that determines skin necrosis. Calciphylaxis has been almost exclusively reported in association with renal failure and altered phosphor-calcium metabolism. Only a few cases have been described in hyperparathyroidism, malignancies, and, recently, cirrhosis. We report a patient that developed calciphylaxis related to end-stage alcoholic cirrhosis, without any alteration in the phosphocalcic and parathyroid hormone metabolisms. Possible contributing factors were repeated albumin infusions and low levels of protein C and S.
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