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Updated: Aug 15, 2026

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
Published on: August 18, 2014
[The mechanographic and biochemical characteristics of induced contractile activity in the frog bladder]
Abstract:
Contractile activity of the frog bladder induced by electrical stimulation of the IX spinal nerve was shown to have a tubocurarine-resistant component. Two main components of the induced motor response were revealed differing from each other in latency, duration and sensitivity to tubocurarine. One of the components seems to be maintained by the activity of cholinergic fibres of the pelvic nerve and ganglion apparatus of the bladder plexus whereas the other component seems to be due to the results of efferent action of sensory terminals on the smooth muscle cells.
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