Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A Hamilton-Jacobi-Bellman approach to high angular resolution diffusion tractography.

Eric Pichon1, Carl-Fredrik Westin, Allen R Tannenbaum

  • 1Georgia Institute of Technology, Atlanta GA 30332, USA. eric@ece.gatech.edu

Medical Image Computing and Computer-Assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
|May 12, 2006
PubMed
Summary

This study introduces a novel white matter tractography framework using high angular resolution diffusion data. The method efficiently maps neural pathways by minimizing directional costs, improving accuracy with high b-value data.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TractoMFormer: A novel streamline-level tractography analysis framework for group classification using deep graph and multi-scale ViT.

NeuroImage·2026
Same author

Study of sex differences in the whole brain white matter using diffusion MRI tractography and suprathreshold fiber cluster statistics.

NeuroImage. Clinical·2026
Same author

Mapping brain tumor microstructure: A multimodal study of diffusion MRI, intraoperative fluorescence, and neuropathology in navigated biopsies.

NeuroImage. Clinical·2025
Same author

Real-world management of unresectable stage III non-small-cell lung cancer: Impact of durvalumab consolidation therapy in French clinical practice.

Respiratory medicine and research·2025
Same author

Effect of a consistent reconstruction algorithm on inter-scanner reproducibility in diffusion MRI.

Medical physics·2025
Same author

Study of Sex Differences in the Whole Brain White Matter Using Diffusion MRI Tractography and Suprathreshold Fiber Cluster Statistics.

bioRxiv : the preprint server for biology·2025

Area of Science:

  • Neuroimaging
  • Diffusion MRI
  • Computational Neuroscience

Background:

  • White matter tractography is crucial for understanding brain connectivity.
  • Existing methods face challenges with high angular resolution diffusion data, particularly regarding anisotropy information.
  • High b-value diffusion MRI offers richer data but often suffers from lower signal-to-noise ratios.

Purpose of the Study:

  • To develop a new framework for white matter tractography in high angular resolution diffusion data.
  • To define a direction-dependent local cost function based on diffusion data.
  • To efficiently solve for minimum cost curves using the Hamilton-Jacobi-Bellman equation.

Main Methods:

  • A direction-dependent local cost is defined for each direction on the unit sphere.

Related Experiment Videos

  • Minimum cost curves are determined by solving the Hamilton-Jacobi-Bellman equation with an efficient algorithm.
  • The framework generalizes classical diffusion tensor-based methods.

    • Main Results:

    • The proposed method successfully utilizes increased angular resolution from high b-value diffusion data.
    • It overcomes limitations of front propagation techniques that can obscure anisotropy information.
    • Implementation and results demonstrate efficacy despite lower signal-to-noise ratios.

    Conclusions:

    • The new framework provides an effective approach for white matter tractography with high angular resolution diffusion data.
    • It offers advantages over traditional methods by preserving anisotropy information.
    • The method shows promise for detailed brain connectivity analysis.