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Updated: Aug 8, 2026

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
Published on: June 3, 2021
Hemodynamics in a cerebral artery before and after the formation of an aneurysm
A Mantha1, C Karmonik, G Benndorf
1Department of Mechanical Engineering, University of Houston, TX 77204-4066, USA.
Abstract:
Using data obtained from 3D digital subtraction angiography acquisitions, computational fluid dynamics techniques were used first to assess hemodynamic factors in geometrically correct models of 3 paraclinoid aneurysms and then again for assessment after virtual removal of the aneurysms and reconstruction of the parent artery. Simulations revealed an area of relatively low and rotating wall shear stresses at the location at which each aneurysm had developed. This phenomenon, to our knowledge, has not been previously described.
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