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Published on: December 15, 2011
Food intolerance and skin prick test in treated and untreated irritable bowel syndrome
Dae-Won Jun1, Oh-Young Lee, Ho-Joo Yoon
1Department of Internal Medicine, College of Medicine, Hanyang University Hospital, Seoul, South Korea 17 Haengdang-dong, Sungdong-ku, Seoul 133-791, Korea.
Aim:
To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens.
Methods:
We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n=31) meeting the Rome II criteria without treatment for IBS, control group (n=30) with no IBS symptoms.
Results:
SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P<0.01). The number of positive SPTs was greater in the IBS group than in the control group (P<0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P=0.03).
Conclusion:
Positive food SPT is higher in IBS patients than in controls.
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