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Detection of Glycosaminoglycans by Polyacrylamide Gel Electrophoresis and Silver Staining
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Detection of Glycosaminoglycans by Polyacrylamide Gel Electrophoresis and Silver Staining

Published on: February 25, 2021

[Qualitative and quantitative determination of urinary glycosaminoglycans in patients with osteochondrodysplasias]

J Sánchez-Corona1, M P Gallegos-Arreola, O Contreras-Sánchez

  • 1División de Genética, Unidad de Investigación Biomédica, CMO, IMSS, Guadalajara, Jalisco, México.

Archivos De Investigacion Medica
|October 1, 1990
PubMed

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Glycosaminoglycans01:23

Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...