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[Antibiotic prophylaxis in operations performed by a microsurgical technic]
Akusherstvo I Ginekologiia
|January 1, 1991
Summary
A single dose of Cephalozoline effectively reduced postoperative infections in women undergoing microsurgical tubal sterilization. This prophylactic antibiotic showed no adverse effects, offering a safe alternative to continuous prophylaxis regimens.
Area of Science:
- Obstetrics and Gynecology
- Surgical Infectious Disease Prevention
Background:
- Postoperative infectious complications are a concern in gynecological microsurgery.
- Continuous antibiotic prophylaxis regimens can be burdensome.
Purpose of the Study:
- To evaluate the efficacy and safety of a single prophylactic dose of Cephalozoline in women undergoing microsurgical tubal sterilization.
- To compare the outcomes with continuous prophylaxis using Ampicillin and Gentamycin.
Main Methods:
- A study involving 50 women receiving a single 2g dose of Cephalozoline.
- Comparison group of 100 women receiving continuous Ampicillin and Gentamycin prophylaxis.
- Microsurgical technique for tubal sterility.
Main Results:
- A reduction in infectious postoperative complications was observed in the Cephalozoline group.
- No disturbances in general state, pulse, or laboratory parameters were noted in the Cephalozoline group.
- No side effects were established for Cephalozoline.
Conclusions:
- A single prophylactic dose of Cephalozoline is effective in reducing postoperative infections after microsurgical tubal sterilization.
- Cephalozoline presents a safe and well-tolerated option for infection prophylaxis in this patient population.