Related Experiment Video

Updated: Aug 8, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

Infective endocarditis in hypertrophic cardiomyopathy--mural and aortic valve vegetations: a case report

Orathai Pachirat1, Virat Klungboonkrong, Cherdchai Tantisirin

  • 1Cardiovascular Disease Division, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Orathai@hotmail.com

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|May 16, 2006
PubMed

Insights

Infective endocarditis (IE) can occur in hypertrophic cardiomyopathy (HCM). Chronic endocardial trauma in HCM may lead to vegetation formation, causing IE.

Area of Science:

  • Cardiology
  • Infectious Diseases

Background:

  • Hypertrophic cardiomyopathy (HCM) is a myocardial disease.
  • Infective endocarditis (IE) is a rare complication of HCM.

Observation:

  • A 46-year-old woman with asymptomatic HCM developed IE.
  • Blood cultures identified Streptococcus viridans.
  • Echocardiography revealed multiple vegetations on the mitral valve, aortic valve, and left ventricle posterior wall.

Findings:

  • The vegetations caused moderate aortic regurgitation.
  • The patient underwent successful aortic valve replacement and vegetation removal.
  • Post-operative antibiotic treatment led to recovery.

Implications:

  • Chronic endocardial trauma in HCM, particularly with outflow tract obstruction, can predispose to IE.
  • Understanding this association is crucial for managing HCM patients.
  • Prompt diagnosis and treatment are essential for favorable outcomes.

More Related Videos

A Surgical Method for Subvalvular Structure Intervention Through a Transaortic Approach in Normal Bama Pigs07:24

A Surgical Method for Subvalvular Structure Intervention Through a Transaortic Approach in Normal Bama Pigs

Published on: March 13, 2026

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...