Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Respirosonography in infants with acute bronchiolitis.

A Tal1, I Sanchez, H Pasterkamp

  • 1Department of Pediatrics, Ben Gurion University, Beersheba, Israel.

American Journal of Diseases of Children (1960)
|December 1, 1991
PubMed
Summary

Respirosonography objectively assessed infant bronchiolitis treatment response to salbutamol (albuterol). Some infants showed significant wheezing reduction, indicating a positive response to this common asthma medication.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of the DEM test as a predictor of reading difficulty.

Journal of optometry·2026
Same author

Improvement of dryness symptoms at the end of the day with artificial tear.

Journal of optometry·2026
Same author

Intraocular pressure values in the Iberian Peninsula: epidemiological study and influencing factors.

Journal of optometry·2025
Same author

A safety evaluation of intermittent high-dose inhaled nitric oxide in viral pneumonia due to COVID-19: a randomised clinical study.

Scientific reports·2024
Same author

Balloon-Expandable Pulmonary Valves for Patched or Native Right Ventricular Outflow Tracts.

Pediatric cardiology·2023
Same author

Image processing tools for the validation of CryoEM maps.

Faraday discussions·2022

Area of Science:

  • Pediatrics
  • Pulmonology
  • Medical Technology

Background:

  • Acute bronchiolitis is a common respiratory infection in infants.
  • Wheezing is a primary symptom, and its objective measurement is crucial for treatment assessment.
  • Salbutamol (albuterol) is frequently used, but its efficacy in bronchiolitis is debated.

Purpose of the Study:

  • To evaluate the effectiveness of nebulized salbutamol in infants with acute bronchiolitis.
  • To assess the utility of respirosonography in objectively measuring treatment response.
  • To analyze breathing patterns and wheezing characteristics in response to salbutamol.

Main Methods:

  • Respirosonography was employed to analyze lung sounds and breathing patterns in 16 infants with acute bronchiolitis.

Related Experiment Videos

  • Wheezing was quantified as the proportion of respiratory time spent wheezing (Tw/Ttot).
  • A positive response was defined as a decrease of ≥10% in Tw/Ttot or a reduction to <2%.

    • Main Results:

    • Seven out of 16 infants showed a positive response to salbutamol, with significant decreases in Tw/Ttot and respiratory rate.
    • Non-responders exhibited no significant change or an increase in Tw/Ttot and respiratory rate.
    • Complex, non-sinusoidal wheezing waveforms were observed in 14 infants, suggesting unique respiratory dynamics.

    Conclusions:

    • Respirosonography offers a noninvasive method for objective assessment of wheezy children.
    • Findings support the clinical use of salbutamol in select infants with bronchiolitis.
    • Objective data from respirosonography can aid in evaluating bronchodilator response in pediatric respiratory conditions.