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Tuberculosis in developing countries.

J D Porter1

  • 1Department of Clinical Sciences, London School of Hygiene and Tropical Medicine.

CDR (London, England : Review)
|November 8, 1991
PubMed
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Tuberculosis (TB) affects millions globally, worsened by HIV co-infection. Research must support national control programs for effective TB strategies.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Tuberculosis (TB) causes 2-3 million deaths annually worldwide.
  • The human immunodeficiency virus (HIV) epidemic exacerbates TB, leading to 'dual infection', particularly in Africa.
  • TB impacts adults in their prime productive years, necessitating renewed focus on control strategies.

Purpose of the Study:

  • To highlight the urgent need for tuberculosis research in developing countries.
  • To emphasize the importance of supporting national tuberculosis control programs.
  • To advocate for research that aids in developing effective tuberculosis control strategies.

Main Methods:

  • This study is a review and analysis of the global tuberculosis situation.
  • It synthesizes data on TB incidence, mortality, and co-infection rates.

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  • It examines the role of HIV in TB reactivation and global spread.

    • Main Results:

    • An estimated 6-8 million people contract TB yearly, with 2-3 million fatalities.
    • In 1990, approximately 3 million individuals had dual HIV/TB infection, with 78% in Africa.
    • TB is a curable and preventable disease, disproportionately affecting productive adult populations.

    Conclusions:

    • Tuberculosis control has become a public health priority due to its significant mortality and the impact of HIV co-infection.
    • Cost-effective interventions for TB are available, underscoring the need for strategic implementation.
    • Research in developing nations should prioritize strengthening national TB control programs and developing robust control strategies.