Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cushing's syndrome.

John Newell-Price1, Xavier Bertagna, Ashley B Grossman

  • 1Division of Clinical Sciences, University of Sheffield, Northern General Hospital, Sheffield, UK. j.newellprice@sheffield.ac.uk

Lancet (London, England)
|May 16, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central serous chorioretinopathy following intramuscular testosterone therapy in prolactinoma.

Oxford medical case reports·2026
Same author

Medical therapy in mild autonomous cortisol secretion.

Journal of the Endocrine Society·2026
Same author

Impact of Osilodrostat on Health-Related Quality of Life in Cushing's Disease: Analysis of Patient-Reported Outcomes From the Phase III LINC 3 and LINC 4 Clinical Trials.

Clinical endocrinology·2026
Same author

[<sup>68</sup>Ga]Ga-DOTATATE uptake in pheochromocytoma/paraganglioma predicts SSTR2 expression by immunohistochemistry: Strongest uptake in head and neck paraganglioma.

European journal of nuclear medicine and molecular imaging·2026
Same author

A novel activating somatic mutation in EPAS1, coding for HIF-2α, in a patient with a paraganglioma and sickle cell disease.

Archives of endocrinology and metabolism·2026
Same author

Multimodal management of hormonal and oncological progression in PTHrP-secreting pancreatic neuroendocrine tumours.

Endocrine oncology (Bristol, England)·2026
Same journal

Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

Lancet (London, England)·2026
Same journal

[<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

Lancet (London, England)·2026
Same journal

Research priorities for characterising Bundibugyo virus.

Lancet (London, England)·2026
Same journal

Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

Lancet (London, England)·2026
Same journal

Dual mobility total hip replacement in fractures: stability promotes patient confidence.

Lancet (London, England)·2026
Same journal

Dual mobility versus standard cups in total hip replacement for displaced femoral neck fractures (Duality): an international, multicentre, randomised, controlled, superiority trial.

Lancet (London, England)·2026
See all related articles

Cushing's syndrome, caused by excess glucocorticoids, presents diagnostic and management challenges. This review covers its causes, symptoms, and offers diagnostic and treatment strategies.

Area of Science:

  • Endocrinology
  • Internal Medicine

Background:

  • Cushing's syndrome arises from prolonged exposure to excessive glucocorticoids.
  • It is associated with substantial morbidity and mortality if left untreated.
  • Accurate diagnosis and effective management remain significant clinical challenges.

Purpose of the Study:

  • To review the current understanding of Cushing's syndrome.
  • To detail its pathogenesis, clinical manifestations, and diagnostic approaches.
  • To provide evidence-based diagnostic algorithms and management recommendations.

Main Methods:

  • Comprehensive literature review of pathogenesis, clinical features, diagnostics, and management of Cushing's syndrome.
  • Analysis of diagnostic and differential diagnostic strategies.

Related Experiment Videos

  • Development of diagnostic algorithms and treatment guidelines.

    • Main Results:

    • Detailed overview of glucocorticoid excess pathophysiology.
    • Summary of characteristic clinical signs and symptoms.
    • Presentation of structured diagnostic pathways and therapeutic options.

    Conclusions:

    • Cushing's syndrome requires careful diagnostic evaluation due to its complexity.
    • Standardized diagnostic algorithms and management protocols are crucial for optimal patient outcomes.
    • This review offers a consolidated resource for clinicians managing this endocrine disorder.