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Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
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Deposition diseases and 3D domain swapping.

Melanie J Bennett1, Michael R Sawaya, David Eisenberg

  • 1Howard Hughes Medical Institute, Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, USA.

Structure (London, England : 1993)
|May 16, 2006
PubMed
Summary

3D domain swapping contributes to protein aggregation in normal cellular structures and diseases. This review examines its role in amyloid fibrils, prion proteins, and macroscopic deposits, highlighting its implication in protein deposition disorders.

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