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Updated: Aug 8, 2026

Measuring Constipation in a Drosophila Model of Parkinson's Disease
Published on: September 22, 2023
Excess burden of constipation in Parkinson's disease: a pilot study
Julie Kaye1, Heather Gage, Alan Kimber
1Guildford and Waverley Primary Care Trust, Guildford, United Kingdom.
Abstract:
An analysis was undertaken of clinic-based questionnaires that asked people with Parkinson's disease and a control group of older people without a known neurological condition about their experiences of constipation. People with Parkinson's disease report higher constipation on a validated objective measure, the Rome criterion (59% vs. 20.9%); a behavioral indicator, laxative-taking (38.4% vs. 14.2%); and subjective self-report of being always or often concerned by it (33.4% vs. 6.1%). Many people with Parkinson's disease experience constipation problems but they may not bring these to the attention of their healthcare providers. More research is required to understand the causes and management options.
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