Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oral mucositis.

C Scully1, S Sonis, P D Diz

  • 1Eastman Dental Institute, University College London, University of London, London, UK. c.scully@eastman.ucl.ac.uk

Oral Diseases
|May 17, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ABC of oral health. Dental damage, sequelae, and prevention.

BMJ (Clinical research ed.)·2000
Same author

ABC of oral health. Oral health and disease.

BMJ (Clinical research ed.)·2000
Same author

Periodontopathic bacteria in English HIV-seropositive persons.

AIDS patient care and STDs·2000
Same author

Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control.

Oral oncology·2000
Same author

Orofacial disease: update for the dental clinical team: 8. Salivary complaints.

Dental update·2000
Same author

Orofacial disease: update for the dental clinical team: 5. Lumps and swellings.

Dental update·2000
Same journal

Structural Validity and Factorial Analysis of the Brazilian Oral Health Impact Profile for Temporomandibular Disorders Instrument.

Oral diseases·2026
Same journal

Effects of Pistacia lentiscus Leaf-Twig and Resin (Mastic) Oils on Salivary Flow in Healthy Individuals.

Oral diseases·2026
Same journal

Oral Delivery of Bioencapsulated CTB-Pro-IGF-1 Enhances Bone Regeneration in a Pre-Clinical Rat Model of Jaw Osteoradionecrosis.

Oral diseases·2026
Same journal

Trends in Stage and Age at Diagnosis of Oral Squamous Cell Carcinoma Over Time: A Systematic Review and Meta-Analysis.

Oral diseases·2026
Same journal

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders.

Oral diseases·2026
Same journal

Authors' Reply "Synchronous Soft-Tissue Lesions in the Oral Cavity in an Adolescent".

Oral diseases·2026
See all related articles

Mucositis and xerostomia are common oral side effects of cancer therapy. Current treatments are limited, but cryotherapy, benzydamine, amifostine, and Palifermin show promise for managing these conditions.

Area of Science:

  • Oncology
  • Oral Medicine
  • Cancer Therapy Complications

Background:

  • Mucositis and xerostomia are frequent oral complications following cancer treatments like radiotherapy, chemotherapy, and stem cell transplantation.
  • These conditions significantly impact patient quality of life, healthcare costs, and survival due to infection risks.

Purpose of the Study:

  • To review the clinical features, prevalence, diagnosis, complications, pathogenesis, prophylaxis, and management of cancer therapy-induced mucositis.
  • To highlight current and emerging interventions for mucositis.

Main Methods:

  • Literature review of clinical features, prevalence, diagnosis, complications, pathogenesis, prophylaxis, and management of mucositis.
  • Analysis of evidence for various preventive and treatment options.

Related Experiment Videos

Main Results:

  • Limited preventive and treatment options exist for mucositis beyond dose reduction.
  • Cryotherapy, topical benzydamine, and amifostine may offer benefits in specific scenarios.
  • Palifermin is approved for mucositis intervention in HSCT patients with hematological malignancies.

Conclusions:

  • Effective management strategies for mucositis remain scarce, necessitating further research and rigorous testing of interventions.
  • Early identification and intervention are crucial for improving patient outcomes and reducing treatment-related morbidity.