Current management of extracranial carotid artery disease

Peter L Faries1, Rabih A Chaer, Sheela Patel

  • 1Division of Vascular Surgery, New York Presbyterian Hospital, Cornell University, New York, NY 10021, USA. plf2001@med.cornell.edu

Insights

Carotid stenosis, a cause of ischemic stroke, is treated by carotid endarterectomy (CEA) or carotid angioplasty and stenting (CAS). This review compares traditional CEA with newer CAS techniques for stroke prevention.

Area of Science:

  • Vascular Surgery
  • Neurology
  • Interventional Cardiology

Background:

  • Stroke is a leading cause of death, with 80% of cases being ischemic.
  • Carotid artery disease accounts for 20-30% of ischemic strokes.
  • Extracranial carotid artery stenosis is a significant risk factor for stroke.

Purpose of the Study:

  • To review traditional management of extracranial carotid artery stenosis.
  • To critically analyze recent results of carotid angioplasty and stenting (CAS).
  • To compare carotid endarterectomy (CEA) with CAS for stroke risk reduction.

Main Methods:

  • Review of multicenter, randomized, controlled trials on CEA.
  • Analysis of recent data on CAS with cerebral protection.
  • Comparative assessment of surgical versus endovascular techniques.

Main Results:

  • Carotid endarterectomy (CEA) significantly reduces stroke risk in severe symptomatic and asymptomatic carotid stenosis.
  • Carotid angioplasty and stenting (CAS) is an alternative for high-surgical-risk patients.
  • CAS is the preferred option for stenoses not amenable to surgery.

Conclusions:

  • Both CEA and CAS are effective in managing carotid stenosis and preventing stroke.
  • CAS offers a less invasive option, particularly for high-risk or surgically inaccessible lesions.
  • The choice between CEA and CAS depends on patient risk factors and lesion characteristics.

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