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Updated: Jul 22, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Current management of extracranial carotid artery disease
Peter L Faries1, Rabih A Chaer, Sheela Patel
1Division of Vascular Surgery, New York Presbyterian Hospital, Cornell University, New York, NY 10021, USA. plf2001@med.cornell.edu
Insights
Carotid stenosis, a cause of ischemic stroke, is treated by carotid endarterectomy (CEA) or carotid angioplasty and stenting (CAS). This review compares traditional CEA with newer CAS techniques for stroke prevention.
Area of Science:
- Vascular Surgery
- Neurology
- Interventional Cardiology
Background:
- Stroke is a leading cause of death, with 80% of cases being ischemic.
- Carotid artery disease accounts for 20-30% of ischemic strokes.
- Extracranial carotid artery stenosis is a significant risk factor for stroke.
Purpose of the Study:
- To review traditional management of extracranial carotid artery stenosis.
- To critically analyze recent results of carotid angioplasty and stenting (CAS).
- To compare carotid endarterectomy (CEA) with CAS for stroke risk reduction.
Main Methods:
- Review of multicenter, randomized, controlled trials on CEA.
- Analysis of recent data on CAS with cerebral protection.
- Comparative assessment of surgical versus endovascular techniques.
Main Results:
- Carotid endarterectomy (CEA) significantly reduces stroke risk in severe symptomatic and asymptomatic carotid stenosis.
- Carotid angioplasty and stenting (CAS) is an alternative for high-surgical-risk patients.
- CAS is the preferred option for stenoses not amenable to surgery.
Conclusions:
- Both CEA and CAS are effective in managing carotid stenosis and preventing stroke.
- CAS offers a less invasive option, particularly for high-risk or surgically inaccessible lesions.
- The choice between CEA and CAS depends on patient risk factors and lesion characteristics.
Abstract:
Stroke is the third most common cause of death in the United States. There are approximately 700,000 strokes/year; 80% are ischemic, and 20-30% of ischemic strokes are secondary to carotid disease. Carotid stenosis is traditionally treated by carotid endarterectomy (CEA). Multicenter, randomized, controlled trials have shown that surgery significantly reduces the risk of ipsilateral stroke in patients with severe symptomatic and asymptomatic carotid stenosis. Endovascular techniques for treating carotid stenosis have been developed over recent years. Carotid angioplasty and stenting (CAS) with cerebral protection has become an alternative to CEA for high-surgical-risk patients and the procedure of choice for stenoses inaccessible by surgery. In this review we summarize the existing data regarding the traditional state of management of extracranial carotid artery stenosis and compare these data to a critical analysis of the recent results of CAS.
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