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Related Experiment Video

Updated: Sep 19, 2025

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An Open-architecture AI Model for CPT Coding in Breast Surgery: Development, Validation, and Prospective Testing.

Mohamad El Moheb1,2, Kristin Putman1, Olivia Sears1

  • 1Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA.

Annals of Surgery
|June 16, 2025
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Summary
This summary is machine-generated.

An open-architecture artificial intelligence (AI) model accurately extracts procedure codes from breast surgery notes, improving efficiency and reducing errors. This AI solution offers a transparent alternative to current coding practices.

Keywords:
CPT codesartificial intelligenceautomationbillingcodingnatural language processingopen-sourceoperative notestransformersworkflow efficiency

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Area of Science:

  • Medical Informatics
  • Artificial Intelligence in Healthcare
  • Surgical Coding Automation

Background:

  • Current operative note coding is inefficient and prone to errors, leading to financial losses and compliance issues.
  • Proprietary, closed-source AI systems hinder adoption due to lack of transparency and validation.
  • An open-architecture AI model is needed for reliable and efficient surgical coding.

Purpose of the Study:

  • To develop, validate, and prospectively test an open-architecture artificial intelligence (AI) model.
  • The AI model aims to extract Current Procedural Terminology (CPT) codes from free-text breast surgery operative notes.
  • To address limitations of current closed-source AI systems in healthcare coding.

Main Methods:

  • Utilized 3259 breast surgery operative notes (July 2017-December 2023) with expert-validated CPT codes as the reference standard.
  • Developed and validated two transformer-based AI models (345M and 3.9B parameters) fine-tuned on operative notes.
  • Evaluated performance using area under the precision-recall curve (AUPRC) and conducted prospective testing on 268 notes.

Main Results:

  • The AI model demonstrated high performance, outperforming human surgeons in CPT code extraction (large model AUPRC: 0.981 vs. surgeon AUPRC: 0.937).
  • Cross-validation showed strong alignment with the reference standard (compact model AUPRC: 0.976).
  • Prospective testing confirmed the AI model's robust real-world performance in extracting procedure codes.

Conclusions:

  • An open-architecture AI model effectively automates CPT code extraction from surgical notes.
  • The developed AI offers a scalable, transparent, and efficient solution for improving surgical coding accuracy.
  • Future research will explore AI's potential to exceed human coder accuracy and reliability.